Finally got to do a real lab outing this year as well as a pseudo-farewell for our RA, Ann who is off to start her joint-PhD with HKU. We wish her all the best and look forward to her return for the 2nd half of the joint PhD!
Sho got awarded the National Natural Science Foundation of China (NSFC) Research Fund for International Excellent Young Scientists to fund the development of RNA modification sequencing via 3rd generation sequencing.
Shenzhen Daily just did an interview with Sho, shining a spotlight on our lab members, the research that we do and why this is important to Shenzhen. Check it out!
The fruits of our amazing collaboration with the Jonathan Goeke lab has yielded xPore, an algorithm that extracts m6A RNA modification sites from nanopore direct-RNA sequencing . Out now in Nature Biotechnology!SZBL press release highlighting our workNature Reviews Genetics highlighting our work
As a joint-postdoc with the Ramanuj DasGupta lab, she will investigate how RNA methylation patterns affect colorectal cancer phenotypes.
It has been a great and productive few years and the Goh lab will always remember its start in Singapore. Here’s to many more great years as we move over to the Institute of Molecular Physiology at the highly funded Shenzhen Bay Laboratory!
Our method for DNA 6mA single-base-resolution sequencing.
Novel RNA-internal m6Am writer, Mettl4 and its role in regulating global splicing patterns through methylating U2 snRNA. A fruitful collaboration with the Xavier Roca lab at Nanyang Technological University. It also turns out that Xavi taught both Casslynn and Irvyn during their undergraduate years!
This will fund a collaboration between us and the Ramanuj DasGupta lab that studies precision oncology.
The collobration with our good friends at the Goke lab, where developed a new algorithm, Xpore to identify RNA modification sites from Nanopore direct RNA sequencing, now summarized in our latest preprint!