Sho Goh Lab

In many ways, modifying RNA is just like formatting text in Microsoft Word

The Goh lab studies how RNA modifications (epitranscriptome) regulate gene expression and cellular processes by developing new technologies to sequence RNA modifications and functionally characterizing novel epitranscriptomic factors that interact with and metabolize RNA modifications. Defects in epitranscriptomic regulation cause a variety of diseases and determining the mechanistic basis that underlie these defects will be crucial for developing effective epitranscriptomic-based therapeutic strategies.

LATEST NEWS

Lab outing 2023
4hr hike up and down Yangtai mountain, culminating in a vendor-sponsored hotpot dinner at CouCou. Perhaps we will do something less intense the next time…
First review article from our lab

Our review about “Heterogeneity of chemical modifications on RNA” written together with Becki Kuang, now out on Biophysical review.
CSHL “Eukaryotic mRNA processing” 2023
This was a home-coming trip for Sho and the first time for both Shahzina and Ann to experience USA. Sho presented some of the lab’s recent work for his talk while Ann got to present her first poster at an international conference.
Shahzina awarded with an independent grant

Congrats to our associate researcher, Shahzaina for obtaining a Guangdong NSFC grant to study the role of RNA modifications in early human embryonic development.
2nd NSFC grant for the lab

Sho got awarded the National Natural Science Foundation of China (NSFC) National High-talent Award for his contributions to the epitranscriptomics field.
Off to RNA society meeting 2023

RNA society meeting is finally coming to Singapore! This is the first international conference where the Goh lab is participating since the pandemic and Ann’s first conference! We’re not presenting this time but are looking forward to all the cool RNA science that will be presented.