In many ways, modifying RNA is just like formatting text in Microsoft Word
The Goh lab studies how RNA modifications (epitranscriptome) regulate gene expression and cellular processes by developing new technologies to sequence RNA modifications and functionally characterizing novel epitranscriptomic factors that interact with and metabolize RNA modifications. Defects in epitranscriptomic regulation cause a variety of diseases and determining the mechanistic basis that underlie these defects will be crucial for developing effective epitranscriptomic-based therapeutic strategies.
LATEST NEWS
- Lab outing 2025
We switched up this year to a poor indoor lab outing, with Lynne and Clare showcasing their karaoke skills, Ann overcoming her fear of scary ride and the whole lab shooting each other down in the VR world.
- Lab outing 2024
Rather than stay in Shenzhen for our annual lab outing, we decided to go to Guangzhou because… reasons… (supposedly the zoo there is better than any in Shenzhen).
- Ann awarded 2024 SZBL Director’s Award
Congratulations to Ann, who at the start of her 3rd year as a PhD student, is 1 of the 4 winners of the SZBL Director’s Award (and it comes with a sweet cash prize)!
- First m6Am reader and new mechanistic role
Our 1st student’s 1st 1st-author paper. Out now in Molecular Cell.
- Lab outing 2023
4hr hike up and down Yangtai mountain, culminating in a vendor-sponsored hotpot dinner at CouCou. Perhaps we will do something less intense the next time…
- First review article from our lab
Our review about “Heterogeneity of chemical modifications on RNA” written together with Becki Kuang, now out on Biophysical review.
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Sho Goh Lab 