Sho Goh Lab

Link to full list of publications

^#Equal contribution *Corresponding author
Lab members underlined

2024

• An HH, Hong Y^#, Goh YT^#, Koh CWQ^#, Kanwal S^#, Zhang Y^#, Lu Z, Yap PML, Neo SP, Wong C-M, Wong AST, Yu Y, Ho JSY, Gunaratne J, Goh WSS*.
  m⁶Am sequesters PCF11 to suppress premature termination and drive neuroblastoma differentiation. Molecular Cell. (Highlighted in a Molecular Cell ‘Preview’ by Akichika & Suzuki)

2021

• Pratanwanich PN*, Yao F^#, Chen Y^#, Koh CWQ^#, Wan YK^#, Hendra C, Poon P, Goh YT, Yap PML, Yuan CJ, Chng WJ, Ng SB, Thiery A, Goh WSS*, Göke J*.
  Identification of differential RNA modifications from nanopore direct RNA sequencing with xPore. Nature Biotechnology. (Highlighted in a Nature Reviews Genetics ‘In Brief’ by Koch)

2020

• Goh WSS*.
  Single-Nucleotide-Resolution Sequencing of N⁶-Methyldeoxyadenosine. Methods in Molecular Biology.

• Goh YT^#, Koh CWQ^#, Sim DY^#, Roca X*, Goh WSS*.
  METTL4 catalyzes N⁶-methylation of adenosines in U2 snRNA to regulate pre-mRNA splicing. Nucleic Acids Research.

2019

• Koh CWQ^#, Goh YT^#, Goh WSS*.
  Atlas of quantitative single-base-resolution N⁶-methyl-adenine methylomes. Nature Communications.

2018

• Koh CWQ^#, Goh YT^#, Toh JDW, Neo SP, Ng SB, Gunaratne J, Gao YG, Quake SR, Burkholder WF, Goh WSS*.
  Single-Nucleotide-Resolution Sequencing of Human N⁶-Methyldeoxyadenosine Reveals Strand-Asymmetric Clusters Associated with SSBP1 on the Mitochondrial Genome. Nucleic Acids Research. (Highlighted as Nucleic Acids Research Breakthrough Article)

2015

• Goh WSS, Falciatori I, Tam OH, Burgess R, Meikar O, Kotaja N, Hammell M, Hannon GJ*.
  piRNA-Directed Cleavage of Meiotic Transcripts Regulates Spermatogenesis. Genes & Development.

2014

• Goh WSS, Seah JWE, Harrison EJ, Chen C, Hammell CM, Hannon GJ*.
  A Genome-Wide RNAi Screen Identifies Factors Required for Distinct Stages of C. elegans piRNA Biogenesis. Genes & Development.
  (Highlighted in a Genes & Development Perspective by Izumi & Tomari).

2010

• Goh WS, Orlov Y, Li J, Clarke ND*.
  Blurring of High-Resolution Data Shows that the Effect of Intrinsic Nucleosome Occupancy on Transcription Factor Binding is Mostly Regional, Not Local. PLoS Computational Biology.